Description
– The topics covered in the six sections of the book are Epidemiology and Environment, Precursors, Pathophysiological Mechanisms, Genetics, Controversies in Schizophrenia, and Treatment. – Reflects the progress made on Schizophrenia since 1986. List of Contents.- Section 1 – Epidemiology and environment.- Schizophrenia and migration.- Childhood meningitis and adult schizophrenia.- The course and outcome of schizophrenia: toward a new social biology of psychosis.- Psychotic features in the general population.Risk factors for what?.- Discussion: Epidemiology and environment.- Section 2 – Precursors of schizophrenia.- Early developmental abnormalities – risk for what?.- Are there specific risk factors for schizophrenia?.- Risk factors for schizophrenia in adolescents.- Cannabis as a causal factor for psychosis – a review of the evidence.- Discussion: Schizophrenia – diverse etiologies,common pathogenesis.- Section 3 – Pathophysiological mechanisms.- Genetic liability, brain structure and symptoms of schizophrenia.- The hippocampus and schizophrenia.- Neuroimaging studies of auditory verbal hallucinations.- Gender differences in schizophrenia.- Section 4 – Genetics.- Searching for inherited causes for schizophrenia:has progress been made?.- Gene expression in psychotic disorders:dissecting the genetic basis of complex neuropsychiatric disorders.- Brain morphological abnormalities in first-degree relatives of schizophrenic patients.- Genetics of schizophrenia and the impact of neuropsychology.- Human genome and the perspectives for schizophrenia.- Discussion: The genetics of psychosis is the genetics of the speciation of Homo sapiens.- Section 5 – Controversies in schizophrenia.- Criminal and antisocial behaviours and schizophrenia: a neglected topic.- The aetiological continuum of psychosis.- When does structural brain change appear in schizophrenia and is it clinically relevant?.- Schizophrenia: developmental, degenerative or both?.- Schizophrenia as a progressive developmental disorder:the evidence and its implications.- Controversies in schizophrenia research:the ‘continuum’ challenge, heterogeneity vs homogeneity, and lifetime developmental-‘neuroprogressive’ trajectory.- Section 6 – Treatment.- What can psychological treatments say about causes in schizophrenia?.- Intervention in the prepsychotic phase of schizophrenia and related disorders: towards effective and safe strategies for earliest intervention in psychotic disorders.- What can molecular imaging tell us about schizophrenia?.- Schizophrenia: treatment issues in the 21stcentury.
