Description
Eine fr den Laboralltag unverzichtbare Informationsquelle zu allen Tierarten – Hunden, Nagetieren und Affen -, die in der experimentellen Toxikologie eingesetzt werden. Jedes Kapitel enthlt Angaben zur Hormonstruktur, Synthese, Sekretion und Rezeptoren; ein spezieller Abschnitt beschftigt sich mit Wirkstoffeffekten und toxikologischen Aspekten. Auch fr Nicht-Endokrinologen, die mit Labortieren arbeiten! About the Author Now a freelance toxicology consultant, David Woodman began his research career investigating the endocrine and physiological sequalae of stress in socially deviant populations. This initial interest in endocrinology and hormones led to many years in the pharmaceutical industry, where the author gained practical experience and expert knowledge in toxicology and drug safety with SmithKline Beecham. Aus dem Inhalt: Organisation of Endocrine Systems; Evolution of Interspecies Variation; The Hypothalamus: Corticotropin Releasing Factor; Growth Hormone Releasing Hormone; Somatostatin; Gonadotrophin Releasing Hormone; Thyrotropin Releasing Hormone; The Pituitary: The Anterior Pituitary: Proopiomelanocortin Related peptides; Luteinizing Hormone and Follicle Stimulating Hormone; Prolactin; Growth Hormone; Thyroid Stimulating Hormone; The Posterior Pituitary: Arginine Vasopressin; Oxytocin; The Thyroid and Parathyroid: Thyroxine, Triiodothyronine and Reverse Triiodothyronine; Calcitonin, Calcitonin Gene Related Peptide; Parathyroid Hormone; The Adrenal: The Adrenal Cortex: Mineralocorticoids; Glucocorticoids; Adrenal Androgens; The Adrenal Medulla: Adrenaline; Noradrenaline; Natriuretic Peptides; The Endocrine Pancreas: Insulin; Glucagon; Islet Amyloid Peptide; Pancreastatin; Pancreatic Polypeptide; Gastrointestinal Hormones: Gastrin; Cholecystokinin; Somatostatin; Vasoactive Intestinal Peptide; Secretin; Motilin; Gastrin Releasing Peptide; Substance P and the Neurokinins; Peptide YY and Neuropeptide Y; Gastric Inhibitory Peptide; Intestinal Glucagon; Neurotensin; Galanin; Gonadal and Reproductive Hormones: Testosterone; Oestrogens and Progesterone; Inhibin, Activin and Follistatin; Relaxin; Placental Lactogens; Endothelin; Erythropoeitin.
