Description
Chapter 1. Pain physiology (defining acute and chronic pain) Chapter 2. Neurobiology of nociception (anatomy of ascending and descending systems) Chapter 3. Genetics of pain and co-occuring symptoms (this could be multiple chapters, each of which will focus on a unique pain type [e.g., Temporomandibular Disorder, Low Back Pain, etc.]) Chapter 4. Sex differences and pain genomics Chapter 5. Systems biology/multi-omis approaches to pain and co-occuring symptoms Chapter 6. Pre-clinical rodent models of pain for genomics studies Chapter 7. Clinical models of experimental pain for genomics studies Chapter 8. Clinical pain genomics research Chapter 9. Pain phenotyping (methods, measures) Chapter 10. Precision health and pain genomics Chapter 11. Exemplars of pain genomics studies (could be multiple chapters) Chapter 12. Roadmap to translation of pain genomics
