Description
This volume covers classic and modern cell and molecular biology of prostate cancer, as well as novel biomarkers, inflammation, centrosome pathologies, microRNAs, cancer initiation novel biomarkers, inflammation, centrosome pathologies, microRNAs, cancer initiation and genetics, epigenetics, mitochondrial dysfunctions and apoptosis, cancer stem cells, angiogenesis and progression to metastasis, and treatment strategies including clinical trials related to prostate cancer. Cell & Molecular Biology of Prostate Cancer is one of two companion books comprehensively addressing the biology and clinical aspects of prostate cancer. Prostate Cancer: Molecular & Diagnostic Imaging and Treatment Stategies, the companion volume, discusses both classic and the most recent imaging approaches including analysis of needle biopsies, applications of nanoparticle probes and peptide-based radiopharmaceuticals for detection, early diagnosis and treatment of prostate cancer. Taken together, these volumes form one comprehensive and invaluable contribution to the literature. Dr. Heide Schatten is a cell and molecular biologist at University of Missouri-Columbia. She specializes in reproduction and cancers of the reproductive systems. She has been involved as scientist adviser to advocates of Cancer Foundations and as a reviewer and study section leader of several Foundations and she has been a reviewer for the DOD prostate cancer program. She has had Cancer Research support and interacted with a large number of well known prostate cancer researchers including many from NIH Comprehensive Cancer Centers. Her publication record shows over 220 original publications, many of which are focused on cell cycle and cytoskeletal abnormalities that are hallmarks for prostate cancer. She has edited several previous books including (2013) Cell and Molecular Biology of Breast Cancer which has over 19,000 downloads. Chapter 1: Brief overview of prostate cancer statistics, grading, diagnosis and treatment strategies.Chapter 2:Novel biomarkers for prostate cancer detection and prognosis.Chapter 3:Inflammation and prostate cancer.Chapter 4:The impact of centrosome pathologies on prostate cancer development and progression.Chapter 5:MicroRNAs as regulators of Prostate Cancer Metastasis.Chapter 6:Epithelial-mesenchymal Transition (EMT) and Prostate Cancer.Chapter 7:The role of multi-parametric MRI and fusion biopsy for the diagnosis of prostate cancer.Chapter 8:Prostate Cancer Treatment Considerations: A Geneticist’s Brief Review of New Treatment Possibilities.
